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KMID : 0352119920080020162
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Journal of Kyung Hee University
1992 Volume.8 No. 2 p.162 ~ p.176
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Effects of Phytolacca Esculenta V. Houtt. On Rats with Acute Renal Failure Induced by Gentamicin Sulfate
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Abstract
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This article is to investigate the effects of Phytolacca esculents V. Houtt. on rats with acute renal failure induced by gentamicin sulfate.
So this experimental research was focused on measuring ① the levels of creatinine, blood urea nitrogen, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, total protein, sodium, potassium, chloride in the serum and ② the levels
of
protein, blood, sodium, potassium chloride, pH, specific gravity and volume in the urine and ③ intake water.
@ES The results were summarize as follows.
@EN 1) While the levels of creatinine and glutamic pyruvic transaminase in the serum were significantly increased, the level of blood urea nitrogen, glutamic oxaloacetic transaminase and chloride in the serum were partially increased and the
level
of
total protein sodium and potassium in the serum were partially decreased on the Phytolacca esculenta V. Houtt. Group.
2) While the urine volume, hematuria and proteinuria were significantly increased, the level of sodium and chloride in the urine were partially increased and the level of potassium and the specific gravity of urine was partilly decreased.
According to the above results, it is shown that Phytolacca esculenta V. Houtt. without refinning had an partial diuretic effect on rats with acute renal failure induced by gentamicin sulfate, but aggravated the glomerular filtration rate and
tubular
reabsorption. So, it is supposed that Phytolacca esculenta V. Houtt. without refinning needs to be carefully on renal disease.
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